Abstract
Purpose: High systemic cholesterol levels are associated with osteoarthritis (OA) development. Novel therapeutic high-intensive cholesterol-lowering therapies have recently been shown to diminish western type diet (WTD) induced atherosclerosis. Here, we investigated the potency of these therapeutic cholesterol-lowering strategies to attenuate OA development in dyslipidemic APOE*3Leiden.CETP mice.
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