Abstract
Experienced clinicians are all too familiar with the unfortunate HIV-infected patient whose CD4-cell count remains unchanged — or even declines — despite complete virologic suppression with antiretroviral therapy (ART). Occasionally, we also see surprisingly low CD4-cell counts among patients who control viral replication without ART (so-called “elite controllers”). In this cross-sectional study, researchers explored immune activation as a possible mechanism for this seemingly …
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