Abstract
• Plasma levels of hs-CRP are higher in subjects who had recently attempted suicide compared to age- and sex-matched healthy subjects. • The lack of correlations between hs-CRP levels measured shortly after the attempted suicide vs. depression severity and other psychological symptoms suggests that inflammation may be specifically related to suicidal behavior. We found significantly higher levels of hs-CRP in 27 subjects who had recently attempted suicide compared to 27 age- and sex-matched healthy subjects. Moreover, the levels of hs-CRP in suicide attempters were not related to background or psychopathological characteristics, nor to the methods of suicide attempt. Our matched case-control study confirms previous observations of high levels of the inflammation marker hs-CRP in patients who have attempted suicide, irrespective of their underlying type and levels of psychopathology.
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