Abstract
Researchers at University Medical Center Utrecht, The Netherlands and other centers review the pathophysiology, clinical relevance, identification, and interpretation of high-frequency oscillations (HFOs, >80Hz) in the epileptic EEG.
Highlights
Researchers at University Medical Center Utrecht, The Netherlands and other centers review the pathophysiology, clinical relevance, identification, and interpretation of high-frequency oscillations (HFOs, >80Hz) in the epileptic EEG
Of 19 pediatric patients with NCSE identified from the database of the Columbia University Epilepsy Center, 6 had periodic lateralized epileptiform discharges (PLEDS), and 1 had generalized PEDS
Prompt recognition of NCSE by continuous EEG monitoring should lead to early treatment and improved prognosis
Summary
Researchers at University Medical Center Utrecht, The Netherlands and other centers review the pathophysiology, clinical relevance, identification, and interpretation of high-frequency oscillations (HFOs, >80Hz) in the epileptic EEG. Risk factors for NCSE in children include a prior clinical seizure and acute cortical imaging abnormality. If NCSE is suspected, continuous EEG monitoring is important in high-risk neonates in the ICU and in children and adolescents with disturbed consciousness and symptoms of encephalopathy.
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