High frequency color doppler ultrasound in early diagnosis of axillary lymph node metastasis of breast cancer

Abstract

Objective To investigate the clinical value of high frequency color doppler ultrasound (CDFI) in early diagnosis of axillary lymph node metastasis of breast cancer. Methods A total of 400 breast cancer patients who received surgical treatment in our hospital were selected from January 2016 to December 2018. All the patients received high frequency color doppler ultrasound examination before the operation. The pathology results were considered as gold standard. 216 breast cancer patients with axillary lymph node metastasis were assigned to the observation group, and 184 breast cancer patients without axillary lymph node metastasis were assigned to the control group. The role of high frequency color doppler ultrasound for the early diagnosis of breast cancer associated with axillary lymph node metastasis was assessed. Results The detection rate of cortical centripetal growth, intra-lymph node calcification, transverse diameter ratio of lymph nodes, and blurred lymph node boundary in the observation group was significantly higher than that in the control group (P< 0.05). The axillary lymph nodes of the observation group were mainly composed of grade 3 blood signal and peripheral blood distribution, while those of the control group were composed of grade 2 blood signal and portal blood distribution. There were statistically significant differences between the two groups (P<0.05). The sensitivity, specificity and accuracy of CDFI in early diagnosis of axillary lymph node metastasis of breast cancer were 91.38%, 86.84% and 86.00% respectively. Conclusion CDFI has high value in early diagnosis of breast cancer with axillary lymph node metastasis. Key words: High frequency color doppler ultrasound; Early diagnosis; Breast cancer; Axillary lymph node metastasis