Abstract
It has been reported that maternal aging is not only characterized by a discernible decrease in ovarian reserve, but also by increasing incidence of cytoplasmic and nuclear aberrations in the oocyte that will lead to aneuploidy in embryos with the consequence of implantation failure. Application of preimplantation genetic diagnosis (PGD) for aneuploidy screening is, therefore, rapidly growing for patients presenting advanced reproductive age (ARA). While information and knowledge on the incidence of chromosomal abnormalities in embryos obtained from the ageing population increases, it remains substantially unknown the frequency of aneuploidy in embryos obtained from young infertile patients (<35 years).
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