Abstract

The tolerance of the vaginal mucosa to high dose rate brachytherapy (HDRB) has not been well described. This is especially important with the use of interstitial implants which are highly patient specific resulting in significant variations in vaginal mucosal dose between patients. Previously we reported on the differential dose to the distal and proximal ano-rectum with HDRB and here, we report on the correlation of vaginal mucosa dose to toxicity as well as quantify the differential tolerance between the proximal and distal vagina.

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