High-Dose Proton Beam Boosted Radiation Therapy in the Management of Non–Skull Base Chondrosarcomas

Abstract

Surgery combined with radiation therapy (RT) has been shown to improve control rates in management of Chondrosarcomas (CS). It is often difficult to safely deliver the high doses required to control these tumors, in the range of 70.2-77.4 Gy, especially in the spinal location using photons. This can however be achieved with proton beam therapy (PBT) due to their physical characteristics of sharp dose fall off at Bragg Peak and distal sparing with no exit dose. The main goal of our study is to evaluate the outcomes of CS patients treated with PBT.