Abstract

High density IgE recognition of the major grass pollen allergen, Phl p 1, revealed with single chain IgE antibody fragments obtained by combinatorial cloning

Highlights

  • Grass pollen is one of the most potent and frequently recognized allergen sources

  • High density IgE recognition of the major grass pollen allergen, Phl p 1, revealed with single chain IgE antibody fragments obtained by combinatorial cloning

  • Methodes Here we investigated the IgE recognition of Phl p 1 using allergen specific single chain IgE antibody fragments (IgE-ScFvs) obtained by combinatorial cloning from a combinatorial IgE-ScFv library constructed from PBMC of a grass pollen allergic patient

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Summary

Open Access

High density IgE recognition of the major grass pollen allergen, Phl p 1, revealed with single chain IgE antibody fragments obtained by combinatorial cloning. Christoph Madritsch*, Elisabeth Gadermaier, Christian Lupinek, Rudolf Valenta, Flicker Sabine. From 5th International Symposium on Molecular Allergology (ISMA 2013) Vienna, Austria. From 5th International Symposium on Molecular Allergology (ISMA 2013) Vienna, Austria. 6-7 December 2013

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