High adiponectin levels in lean Arab women compared to Asian women.

Mohamed Abu-Farha,Naser Elkum,Kazem Behbehani

doi:10.1186/s40364-015-0032-5

Mohamed Abu-Farha, Naser Elkum + Show 1 more

Open Access

https://doi.org/10.1186/s40364-015-0032-5

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Abstract

Adiponectin has been recognized as a potent regulator of metabolism possessing anti-inflammatory and anti-atherogenic functions and inversely associated with increasing incidents of type 2 diabetes and obesity. In this study, we investigated the changes in adiponectin level of 193 Arab and 132 Asian women were compared. Overall, Arab women had statistically significant higher levels of adiponectin 17.84 (1.047) μg/mL than Asians 12.87 (1.049) μg/mL. In conclusion, our data demonstrates that Arab women poses high adiponectin level compared to Asians and the protective role of adiponectin in Arab women against metabolic disorders requires further attention.

Highlights

Adiponectin has been recognized as a potent regulator of metabolism possessing anti-inflammatory and anti-atherogenic functions and inversely associated with increasing incidents of type 2 diabetes and obesity
Plasma level of adiponectin of 193 Arab and 132 Asian women living in Kuwait was assessed using the multiplexing immunobead array platform (Luminex, Austin, TX) using a 2-Plex kit (BioRad, Hercules, CA)
* Correspondence: nelkum@hotmail.com 3Clinical Epidemiology, Sidra Medical and Research Center, 26999, Doha, Qatar Full list of author information is available at the end of the article overweight, ≥30 was considered obese)

Summary

Introduction

Adiponectin has been recognized as a potent regulator of metabolism possessing anti-inflammatory and anti-atherogenic functions and inversely associated with increasing incidents of type 2 diabetes and obesity. Different levels of adiponectin have been reported in different ethnicities. Asians have a lower adiponectin plasma level than Caucasians, which is consistent with the increased risk of metabolic disorders among Asians [1]. Plasma level of adiponectin of 193 Arab and 132 Asian women living in Kuwait was assessed using the multiplexing immunobead array platform (Luminex, Austin, TX) using a 2-Plex kit (BioRad, Hercules, CA).

Results

Conclusion