Abstract
Hydroxyurea is a chemotherapeutic agent which is used in the management of myeloproliferative disorders. Mucocutaneous adverse effects and nail hyperpigmentation can be observed in long-term treatment. Cases of hydroxyurea-induced melanonychia develop predominantly in female patients and the most common pattern is longitudinal bands. Here we present a case of 65-year-old woman patient that has longitudinal melanonychia on the nails of the hands, observed at the eighteenth month of the treatment of hydroxyurea. By means of this case, it is aimed to be aware of the cutaneous side effects of hydroxyurea which is commonly used in myeloproliferative disorders
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