Abstract

To discuss the effective interactions between macroanions, such as acidic proteins, the radial distribution function between macroanions, gMM(r), was calculated using an integral equation theory with a charged hard spheres model under weak coupling conditions. Explicit and implicit solvent models were examined. The gMM(r) for the explicit solvent model indicated a significant peak at the contact distance, which was caused by the translational motion of solvent molecules. In contrast, the gMM(r) for the implicit solvent model did not indicate any significant peak at the distance because of no explicit solvent particles. Although there was a significant difference in the gMM(r) for the explicit and implicit models, the structure factor SMM(k) was nearly the same and the shapes and peak shifts caused by macroanion concentration changes were also similar to the experimental results. To reproduce the first sharp peak in gMM(r), the structure factor SMM(k) provided by scattering experiments was not sufficiently long for standard analyses. This showed that the results provided by conventional small-angle scattering experiments cannot deny the existence of a first sharp peak in gMM(r).

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.