Abstract
A molecular crystallography approach reveals the existence of a hidden order in GroEL-GroES-(ADP)(7). The new crystallographic symmetry concepts required are first illustrated for a hypothetical planar molecule. Their application to the chaperonin complex leads to molecular forms with vertices having integral coordinates (the indices) with respect to a symmetry-adapted basis and to folding points approximated by ideal C(alpha) positions with rational indices connected by integral scale-rotations, just as for the vertices of the molecular forms. The Mg(+2)-ions at nucleotide binding sites are symmetry-related in a similar way to C(alpha)'s folding points.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
