Abstract
AbstractInstallation of an alkyl chain at a specified position in the aromatic ring via metal‐free catalysis is very important. In this regard, we have developed a facile metal‐free, extremely selective, user‐friendly, environmentally benign and cost‐effective Friedel‐Crafts (FC) alkylation protocol for 2‐oxindoles and anilines with donor‐acceptor cyclopropanes. Real‐time NMR studies reveal that the transformation is governed by the cooperative catalysis of Brønsted acid (TfOH) and HFIP, which facilitates the nucleophilic attack on donor‐acceptor cyclopropanes from 2‐oxindoles and anilines.magnified image
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