Abstract
Objective: Hypothyroidism (HT) is associated with increasing risk for all-cause and cardiovascular mortality. HT has multiple adverse effects on the cardiovascular system through dyslipidaemia, diastolic hypertension, altered coagulation status, endothelial dysfunction, and arterial stiffness. Heart fatty acid binding protein (H-FABP) is an intracellular molecule engaged in the transport of fatty acids through the myocardial cytoplasm and a rapid marker of myocardial injury. The aims of this study are to detect serum concentrations of H-FABP in patient with subclinic hypothroidism (SCH) and overt hypothyroidism (OH) and to investigate its associations with CIMT, metabolic parameters and subclinical atherosclerosis.
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