Abstract

Hexamethylenetetramine (HMTA) is a heterocyclic organic compound having a symmetric tetrahedral cage-like structure, whose four ‘corners’ are nitrogen atoms and ‘edges’ are methylene groups. It is also known as hex­amine. It behaves like an amine base and known for its versatile role in organic chemistry. It plays an important role in formylation (Duff reaction), [¹] [²] conversion of benzyl ­halides into corresponding aldehydes (Sommelet reaction), [³] and synthesis of amines (Delépine reaction). [4]

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