Abstract
An efficient Keggin-type heteropolyacid-catalyzed reaction for the synthesis of 2-pyridone derivatives using amines, acetylenic esters, and malonic esters or acid is reported. Optimum conditions were developed in i-PrOH at 60–100 °C. The activity of immobilized H3PW12O40 on the traditional amorphous silica was also examined.
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