Abstract

New oxazolone‐based heteromultifunctional linkers were synthesized using a zinc‐mediated double functionalization of nitriles as the key step. The orthogonality of the functional groups displayed by this original scaffold was demonstrated by conducting sequential or simultaneous multi‐component reactions with amines (oxazolone ring opening), thiols (thiol‐ene radical reaction) and azides (Cu‐catalyzed azide–alkyne coupling), in respect to the concept of click chemistry.

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