Abstract
Equimolar and non-equimolar heterocompounds of amino acids are examined with a common approach considering their molecular dimers, side chain structures and conformations.
Highlights
Many organic substances are chiral molecules, which can exist as levo and dextrorotatory optical antipodes
We (1) introduce a classification of discrete compounds formed in chiral systems, (2) discuss the chiral molecular packing in crystal structures of amino acids and their equimolar heteromolecular compounds, and (3) present detailed studies of mainly two levorotatory amino acid systems, L-valine–L-leucine and L-valine– L-isoleucine, as examples of binary chiral systems forming non-equimolar heteromolecular compounds
The consideration is complicated by the lack of a common approach for terminology and allocation of compounds with chiral molecules in the literature
Summary
Many organic substances are chiral molecules, which can exist as levo and dextrorotatory optical antipodes. These molecular entities being mirror images of each other and non-superposable are called enantiomers.[1] In their molecular structures, enantiomers possess a chiral element, which in most cases is a chiral center and less frequently, a chiral plane or a chiral axis. The great diversity of amino acids and relatively simple structures of their molecules made them already model compounds, for example, for the determination of hydrogen bond lengths in proteins and other biopolymers.[7,8]. We (1) introduce a classification of discrete compounds formed in chiral systems (section 2), (2) discuss the chiral molecular packing in crystal structures of amino acids and their equimolar heteromolecular compounds (sections 3 and 4), and (3) present detailed studies of mainly two levorotatory amino acid systems, L-valine–L-leucine and L-valine– L-isoleucine, as examples of binary chiral systems forming non-equimolar heteromolecular compounds (section 5)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
