Heterogeneous patterns of posttraumatic stress symptoms and depression in cancer patients

Abstract

BackgroundStudies suggest that posttraumatic stress symptoms (PTSSs) and depression are common psychological outcomes in cancer patients and have high co-occurring prevalence. However, it is unclear whether PTSSs and depression always co-occur in cancer patients. This study aimed to clarify these co-occurring patterns. MethodsParticipants were 270 cancer patients who completed self-report questionnaires. Latent profile analysis was used to examine co-occurring patterns of PTSSs and depression. ResultsThe results indicated four patient types: a low symptom group (n = 34, 13.0%), a depression symptom group (n = 99, 37.8%), a moderate co-occurring symptom group (n = 97, 37.0%), and a severe co-occurring symptom group (n = 32, 12.2%). Multinomial logistic regression was used to examine the role of social support, core belief challenge, and intrusive rumination in differentiating these groups. Intrusive rumination was more likely to be associated with depression symptoms, moderate co-occurring symptoms, and severe co-occurring symptoms. Core belief challenge was more likely to be associated with both moderate and severe co-occurring symptoms, and social support was less likely to be associated with moderate co-occurring symptoms. LimitationsAll variables were measured using self-report scales. ConclusionsThe coexisting patterns of PTSSs and depression in cancer patients are heterogeneous. Core belief challenge and intrusive rumination effectively differentiated PTSSs and depression patterns. Social support differentiated the low symptom group from the moderate co-occurring symptom group.