Heterogeneous enantioselective catalyzed carbonyl- and imino-ene reactions using copper bis(oxazoline) zeolite Y.

Abstract

A recovery discovery: A simple pathway for the synthesis of α-hydroxy and α-amino carbonyl compounds with good yields and high enantioselection is provided by the first heterogeneously catalyzed enantioselective carbonyl-ene and imino-ene reactions. The catalyst is a bis(oxazoline)-modified CuH zeolite Y (Cu-HY)system (see scheme; Rox=CH3,H; Rbrg=Ph,C(CH3)3), which can easily be recovered and reused.