Abstract
Supported catalysts, Rh/SiO 2, Ru/SiO 2, Pd/SiO 2, Pt/SiO 2 and Pd/C reduce methyloate of 3α-acetyl-11,12-dioxo-5β-cholan-24-oic acid 1 into the vicinal hydroxyketone 11-oxo,12β-OH 2 in 100% chemo-, regio- and diastereoselectivity at 100% of conversion.
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