Abstract
The Müller cell membranes of the rabbit retina were investigated by means of freeze-fracturing. Orthogonal arrays of particles (OAP) were found almost exclusively where the Müller cell endfoot had direct contact with the vitreous body. In the center of the retina where the Müller cells are long and thin, the density of OAP was about 170/microns2. In the periphery where the Müller cells are shorter and thicker, the density of OAP was about 20/microns2. In this area, only half of the Müller cell endfeet were equipped with OAP. The results are discussed with respect to electrophysiological studies on the role of various K+ channels in glial cells. It is proposed that OAP might possibly represent specialized 'maxi'-K+ channels which are involved in K+ spatial buffering of the extracellular space.
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