Abstract
Endothelial plasma membranes in rat thoracic aorta contain a spectrum of junctional specializations detectable in freeze-fracture replicas. While plasma membranes of some endothelial cells show single- or double-stranded tight junctions that form continuous belts, tight junctional strands are widely discontinuous in other endothelial cells. Gap junctions are frequent, separately or in association with tight junctions in the plasma membranes of all aortic endothelial cells. Heterogeneous organization of cell junctions in aortic endothelium may represent sites of differing paracellular permeability.
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