Abstract
At the electron microscopical level various types of monocytes and macrophages can be recognized after application of a cytochemical method for the demonstration of peroxidatic (PO) activity. PO activity is found in granules of monocytes and exudate macrophages, in the rough endoplasmic reticulum (RER) and nuclear envelope of resident macrophages and in granules as well as in the RER and nuclear envelope of exudate-resident macrophages. PO-negative macrophages lack PO activity (1). All of these cell types occur in the peritoneal cavity after stimulation with various agents and can be generated in bone marrow cultures if the appropriate growth factors are present (2–4).
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