Abstract

Hydrolysis of ethyl pteridine-4-carboxylate gave the corresponding carboxylic acid as a 5,6:7,8-dihydrated species which could not be dehydrated without decomposition. Syntheses of pteridine-4-carboxamide, N-ethylpteridine-4-carboxamide, 6,7-dimethylpteridine-4-carboxamide, and pteridine-4-carbonitrile are described and the covalent hydration behaviour of these compounds is discussed.

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