Heterocycles with a Stereogenic Phosphorus or Sulfur Atom Derived from Aminoalcohols or Aminonaphthols

Abstract

This chapter presents the synthesis of heterocycles with a stereogenic phosphorus or sulfur atom derived from aminoalcohols or aminonaphthols, which has been reported recently (usually after 2002). It also contains selected references to the earlier papers and is divided into three sections, describing methods of synthesis of the three particular classes of heterocyclic derivatives. The first two are devoted to heterocycles with a stereogenic phosphorus atom and discuss the protocols for the preparation of 1,3,2-oxazaphospholanes (1,3,2-oxazaphospholidines) with a tri- and tetracoordinated phosphorus atom, 1,3,2-oxazaphosphorinanes and larger rings containing a stereogenic phosphorus atom forming part of the nitrogen-phosphorus-oxygen (NPO) grouping. The third section concerning heterocycles with a stereogenic sulfur atom describes the synthesis of all kinds of 1,2,3-oxathiazolidine 2-oxides and tetrahydro-1,2,3-oxathiazine-2-oxides.