Abstract

A series of ethyl 2-(substituted)-9-cyclopropyl- 4-fluoro-6-oxo-1H-imidazo(4,5-h)quinoline-7-carboxylates has been prepared from ethyl 7,8-diamino-1,4-dihydro- quinoline-3-carboxylate via thermally induced reactions with model alkanoic acids or via microwave-assisted cyclocondensation with some arene carboxaldehydes. Acid-catalysed hydrolysis of the resulting ester derivatives furnished the corresponding imidazoquinoline-7-carbox- ylic acids. The structures of these new acid and ester derivatives are based on microanalytical and spectral (IR, MS, and NMR) data.

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