Abstract
A novel series of heterocyclic systems fused coumarins and chromones were efficiently synthesized from chemical transformations of 6,8‐dimethylchromone‐3‐carbonitrile (1) with a variety of carbon nucleophilic reagents. Ring opening ring closure reactions of carbonitrile 1 with cyanoacetohydrazide, malononitrile dimer (2‐aminoprop‐1‐ene‐1,1,3‐tricarbonitrile), and isomeric cyclohexanediones led to a diversity of coumarins and chromones fused nitrogen heterocyclic systems. Also, 1‐ethyl‐4‐hydroxyquinolin‐2(1H)‐one (13) and 6‐ethyl‐4‐hydroxypyrano[3,2‐c]quinoline‐2,5(6H)‐dione (14) are chemical equivalent towards carbonitrile 1 leading to benzo [h]chromeno[2,3‐b][1, 6] naphthyridine derivative 15. Structures of the new synthesized products were deduced on the basis of their analytical and spectral data.
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