Abstract
Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by a singlegene mutation, and is associated with a mild-to-moderate intellectual disability in males. Due to the well-defined neurobiological origin, FXS is frequently used as a model to study the effects of genetic abnormalities on cognitive development and behavior. A central question in this line of research is why some cognitive functions are more affected than others. To date, most studies have focused on the characterization of the higher-level cognitive processes, whereas the perceptual characteristics of information processing in the brain remain understudied. Importantly, these lower-level information processing characteristics can further our understanding of those neurobiological processes that go astray in FXS. Additionally, these investigations will reveal important information on the quality of cognitive information processing in neurodevelopmental disorders, and demonstrate that cognitive functioning in neurodevelopmental disorders cannot solely be interpreted in terms of intact vs. spared cognitive functions.
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