Abstract
Objective: Herpes simplex virus (HSV) esophagitis is rare in immunocompetent patients, with only 36 reported adult cases to date. The aim of this case series is to identify characteristics of immunocompetent patients at risk of developing HSV esophagitis, study the natural progression, and evaluate the efficacy of antiviral treatment. Methods: A retrospective cohort study was performed on all consecutive HSV esophagitis cases diagnosed from 2003-to-2007. Twenty-six cases were initially identified with histopathology proven HSV esophagitis.
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