Abstract
an HSV-1 limbic encephalitis. One patient (case 3) had neurosurgical resection of a right temporal glioblastoma 10 days before the onset of encephalitic illness. By 16 days after surgery, magnetic resonance imaging showed bilateral asymmetric temporal, insular, and right cingulate gyrus abnormal fluid-attenuated inversion recovery signal, consistent with HSV encephalitis,despitetreatment.Asecond patient (case 4) had encephalitis withabnormal fluid-attenuatedinversionrecoverysignalintheleftanterior and medial temporal, insular, and inferofrontalareasonMRI,moretypical of HSV-1 encephalitis. The remaining 3 patients had generalized encephalitis with altered mental status, no focal neurologic findings, and normal or nonspecific neuroimaging findings. Despite acyclovir treatment, outcomes were poor. Our case series highlights the following key points: (1) HSV-2 encephalitis occurs in elderly, immunocompromised patients, (2) the presentation may be clinically indistinguishable from HSV-1 encephalitis in adults, and (3) the prognosis of immunocompromised adults with HSV-2 encephalitis may be unfavorable, even when antiviral therapy is administered. In 1993 in Sweden, Aurelius et al 1
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
