Abstract
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Highlights
The successful outcome of a case of herpes simplex encephalitis (HSE) in a pregnant woman at 29 weeks gestation is reported from the Depts of Neurology and Gynecology and Obstetrics, Royal Perth Hospital and the State Health Lab Services, Perth, Western Australia
COMMENT: This case of HSE is the sixth to be reported in pregnancy and the second to survive
A 17-month-old boy with HZO and delayed contralateral hemiparesis following intrauterine varicella exposure is reported from the Dept of Neurology, Univ Texas Med Sch, Houston, TX
Summary
The successful outcome of a case of herpes simplex encephalitis (HSE) in a pregnant woman at 29 weeks gestation is reported from the Depts of Neurology and Gynecology and Obstetrics, Royal Perth Hospital and the State Health Lab Services, Perth, Western Australia. Hie diagnosis was suspected from the clinical presentation with fever, headache, stupor, generalized convulsion, a focal EEG, and a hypodense area in the right temporal lobe on CT. It was confirmed retrospectively from evidence of specific antibody production in the CSF. Acyclovir 800 mg/d IV every 8 hours and in a reducing regime was continued for 22 days She recovered after 2 months and delivered a normal unaffected baby. Herpes simplex encephalitis in third trimester of pregnancy: successful outcome for mother and child. One previous fetus has survived a pregnancy complicated by HSE and the mother, treated with idoxuridine, died 5 days postpartum.
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