Abstract
About a year ago1, 2, 3, 4 the writer mentioned the occurrence of several mice with kidney defects that were descendants in the sixth and subsequent generations of certain x-rayed animals in which an attempt had been made to alter the germ plasm by physical agents. For details concerning the work leading to these studies, and the data so far recorded, the reader is referred to the references given below.The present communication deals with the results of 1817 autopsies of the descendants of mice with visceral abnormalities, which are mainly of the urinary system but are also associated with other visceral disturbances. Preliminary genetic results are also given to show the nature of the inheritance of these abnormalities. The following is a brief summary of the types of visceral abnormalities so far observed with the number of individuals in each group recorded in parenthesis:A. In adult animals: 1. Kidneys moderately unequal in size, with no hypertrophy of the larger (5). 2. One kidney nearly completely ...
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