Abstract

患者女性,54岁,遗传性球形红细胞增多症合并恶性梗阻性黄疸致超高胆红素血症。入院时总胆红素高达1 612.8 μmol/L,MRI示肝外胆管及胆总管扩张,经内镜逆行胰胆管造影(ERCP)置入支架解除梗阻。术后半个月因支架脱落,胆红素波动性上升,合并感染后溶血危象。再次经ERCP置入支架,经胆道镜观察狭窄段黏膜大致正常,经综合治疗患者情况稳定后行胆囊及脾切除术。术后病理未见明显异常,好转出院。随后因胆道感染再次入院经ERCP置入支架,于胆囊窝处穿刺病理提示腺癌。

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