Abstract
Palmoplantar keratosis or palmoplantar keratoderma (PPK) constitutes a heterogeneous group of disorders characterized by excessive epidermal thickening of the palms and soles of affected individuals [1]. PPK can be characterized as either inherited or acquired. Transgredient PPK extends beyond palmoplantar skin, contiguously or as callosities on pressure points on the fingers or knuckles, or elsewhere. Typical pathohistological findings of PPK are orthokeratotic hyperkeratosis, hyperor hypogranulosis and acanthosis. These changes are non-specific and found in many types of PPK.
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