Abstract

This is the 6th case of hereditary hemorrhagic telangiectasia associated with hepatic cirrhosis in which sufficient evidence was available to exclude reasonably known causes of chronic liver disease. Consequently it may be that the development of cirrhosis was a direct result of hereditary hemorrhagic telangiectasia. In support of this view, it was noted that not only was there very extensive involvement of the liver by telangiectatic malformations, but that, in addition, these malformations were found within the fibrous septa in the liver. It is suggested that the cirrhosis in hereditary hemorrhagic telangiectasia may be the result of extensive involvement of the liver by telangiectases although no definite cause and effect conclusions can be reached.

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