Abstract

THE HEREDITARY BLEEDING DISEASES constitute a veritable storehouse of valuable, potential, untapped information for unravelling many problems of human genetics and for probing the intricate coagulation mechanism of the blood and of hemostasis. More than 12 different hemorrhagic diseases are now known to be congenital in origin. Laboratory tests have become available for characterizing each of these entities with a relatively high degree of precision and for exploring their basic defect. the sex-linked recessive type. Von Willebrand's disease, known also as pseudohemophilia A, and telangiectasia or Rendu-Osler's disease represent the autosomal dominant type. Most of the remaining bleeding diseases are inherited as autosomal recessives as shown in the table. In this group are congenital thrombocytopenia, hypofibrinogenemia, hypoprothrombinemia, and deficiencies of <h3>Type and Incidence of Inheritance</h3>

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