Hereditary Aspects of Urologic Cancer

Abstract

The current status of genetic research at the molecular biology level is reviewed as it applies to the hereditary aspects of urogenital cancer. An introductory overview of tumorigenesis as a multistep process with interactions between the host and environment is followed by separate discussions of hereditary and genetic alterations in the five major urologic cancers: prostate, urothelial, testicular, renal cell, and Wilms’ tumor.