Abstract
Angioedema is defined as ill-defined, localized, self-limiting facial, oral, laryngeal, genital, or peripheral swelling or abdominal pain in response to release of vasoactive mediators (bradykinin). It is more common in women, often associated with urticaria, and affects 15 percent of the population. Angioedema occurs in a variety of forms–idiopathic, allergic, hereditary or acquired, cytokine or autoimmune–thyroid-disease associated, physically or medication-induced angioedema (Figure 1).1
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