Abstract

Agroup of physicians treated victims of the 1918 influenza pandemic with botanical medicines and the treatments were very successful. This article reviews some of the botanicals that were used to treat patients who had influenza. It also reviews research indicating that herbs can counteract the cytokine dysregulation induced by severe types of influenza. Coverage includes Gelsemium sempervirens (gelsemium root; also known as yellow jasmine and yellow jessamine), Eupatorium perfoliatum (boneset; also known as thoroughwort and Indian sage), Actea racemosa (black cohosh; also known as macrotys; formerly Cimicifuga racemosa), Asclepias tuberosa (pleurisy root; also known as butterfly weed), and Atropa belladonna (belladonna) as well as the roles that interleukin (IL)-6, interferon-γ–inducible protein (IP)-10, cytokines, and chemokines play in influenza.

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