Abstract

Based on literature studies, ethnobotanical and ethnomedicinal surveys in China, we recorded 1524 taxa of plants used for oral diseases from 36 ethnic groups and Han Chinese. They belong to 164 families and 599 genera. An inventory had been finished with names (local name, Chinese name and scientific name), botanical description, habitat and distribution, taste or smell, functions, parts used, preparing method, other uses and ethnobotanical information. Southwest China is the richest region with most species of medicinal plants, and with plentiful traditional knowledge to use herbal medicine to treat oral disorders. More species will be discovered in southwest China, particularly in Yunnan's ethnic communities. A few species used by ethnic people for treating oral disorders were selected for phytochemical and pharmacological studies. For instance, the stems of Piper boehmeriaefolium (Piperaceae) have been used to treat toothache by the De'ang people in southwest Yunnan. We isolated 30 compounds from Piper boehmeriaefolium, in which 8 are new ones. Most of theses compounds are alkaloids of amides, which showed good biological activities. This study was supported by National Natural Science Foundation of China (31161140345), the Ministry of Science & Technology of China (2012FY110300), the Ministry of Education of China (B08044) and the Minzu University of China (YLDX01013).

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