Abstract
The exposure and heterogeneity of the new virus is increasing at an alarming rate. Unexpected outburst of Coronavirus has upraised various serious questions about their management using conventional diagnostic and medication measures. Vaccines help to train the immune system to avert people from developing disease, such as Covid-19. If sufficient people become immune then the would not be able to escalate effectively. Since, there are no specific vaccines or treatment for COVID-19, so the researchers are competing to find more about it. From various review it has been found that the name coronavirus is derived from Latin corona, meaning “wreath” or “crown”. The name point out the characteristics aspect of virions (the infective form of the virus), which possess fringe of large, bulbous surface projections producing an image reminiscent of a crown. Coronavirus are large pleomorphic spherical particles with bulbous surface projections. The average diameter of the virus particles is around 120 nm. Infection start about when the viral spike (S) glycoprotein binds to the complementary host cell receptor. After binding, a protease of the host cell splits and activates the receptor-attached spike protein.
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