Herbal based nanoemulsions in psoriasis therapy: A review

Abstract

IntroductionPsoriasis is a chronic, non-communicable, painful, disfiguring, and disabling disease of skin and joints. According to the National psoriasis foundation, psoriasis affected about 0.08–12%, globally worldwide hassle. Herbal medicine as a promising approach for anti-psoriatic because they are safe, effective, inexpensive and minimal side effects but still they have lesser bioavailability, skin penetration and patient compliance are the limitation to the treatment. Materials and methodsThe literatures and data for the manuscript were searched in the various search engines such as web of science, PubMed, and Scopus for the management of psoriasis. A literature review revealed that herbal-based nanoemulsion with anti-psoriatic potential with enhanced drug loading capacity, therapeutic effects, stability and reduced dosage. ResultNanoemulsions-based drug delivery systems have been considered encouraging vehicles for enhancing the therapeutic potentials of drugs for skin and topical application. Various novel nanotechnology-based drug delivery systems have been explored such as nanoemulsions, hydrogel, niosomes, ethosomes, dendrimers, nanosuspension, solid lipid nanoparticles, nanostructured lipid carriers, liposomes etc. used in this field to overcome these problems. DiscussionsNumerous psoriatic patients are being treated with herbal medicines with lesser adverse effects. Clinicians should be aware of herbal or medicinal plants used in psoriasis and the side effects related to them. Therefore, the present review article features the various aspects of nanoemulsions as a novel drug delivery system for the management of psoriatic skin through herbal medicines.