Herbal and Integrative Medicine-Associated Improvement of Viral-Induced Cervical and Vaginal Disorders: Case Report

Abstract

Objective: Cervical cancer is a serious challenge, and pharmacologic nonsurgical treatment of precursor human papilloma virus (HPV) conditions does not exist. The Centers for Disease Control and Prevention (CDC) estimates 36,500 new cases of (HPV)-associated cancers per year. The purpose of this report is to illustrate a method that could eliminate HPV positivity to control precancerous lesions before they develop carcinoma. Eighty-six percent of cervical cancers contain HPV as a likely causal factor. Design/Setting: Two patients sought private practice integrative medicine: one for chronic HPV-induced cervical dysplasia, the other with lichen sclerosis post squamous cell carcinoma (SCC). Methods: The two patients were included because they asked for help with their conditions, since no previous medical help was either offered or successful. Patients were treated with a systematic integrative approach, designed to normalize leaky gut, and microbiome to reduce systemic antigenic stimulation. Also, berberine and curcumin were given, based on in vitro data on their effectiveness for treating HPV-induced oncogenic changes in cells. Those herbal derivatives were obtained from an organic chemist who maintained strict quality control. Results: A patient with oncogenic HPV-induced chronic severe cervical dysplasia had a dramatic improvement of dysplasia and HPV positivity. The patient with lichen sclerosis and atrophicus had a 75% improvement in the appearance of her condition, and her suspected SCC was in situ. Discussion: From this limited case report, it appears that a combination of integrative methods, plus curcumin and berberine, can clear oncogenic HPV and reverse dysplastic and oncogenic changes in the cervix as well as autoimmune changes in the vaginal area. Conclusion: The combination of integrative methods and curcumin and berberine helped patients with oncogenic HPV-induced cervical dysplasia and autoimmune and cancer-forming lichen sclerosis. Considering the high prevalence of HPV-induced cervical dysplasia, and the lack of treatment, this study should be repeated at a larger level.