Abstract
This study was conducted to study the hepcidin gene polymorphism and its effect in patients with β-thalassemia. Blood samples were collected from patients visiting (for the Center for Genetic Blood Diseases - Thalassemia) in Al-Diwaniyah for ages (15-35) for males. The results were as follows: The present study enrolled 50 patients with Thalasemia and 40 apparently healthy subjects. The mean age of patients was 39.31 ± 12.89 and that of control subjects was 28.74 ± 10.77 years and there was no significant difference between patients and control subjects in mean age (P = 0.277). Again, there was no significant difference in the frequency distribution of patients and control subjects according to age (P = 0.0125). Patients’ group included < 20 years, n (%) in patients 17 (34.00 %), and in control 7 (20.00 %), whereas, 20-25 years, n (%) in patients 6 (12.00%) and in control 7 (20.00 %), whereas, 30-35 years, n (%) in patients 8 (16.00%) and in control 3 (8.57 %).
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