Hepatotoxicidad por esteroides anabólicos androgénicos, reporte de 2 casos en Uruguay

Yéssica Pontet,Nelia Hernández,Alfonso Calleri

doi:10.25184/anfamed2018v5n2a4

Abstract

Illicit consumption of anabolic-androgenic steroids for aesthetic purposes has increased in recent years. Hepatocellular damage is more frequent, but cholestasis is more dangerous and may be associated with renal failure. The clinical records of two young men, amateur athletes who consulted for jaundice in the last year and initially denied its consumption, are described. Except for the drug interruption, hepatotoxicity by anabolics has no specific treatment. Usually presented as cholestatic liver disease and renal failure, case reports are fundamental to characterize its clinical-evolutionary presentation. This may also allow clinicians to firmly consider diagnosis even when the patient denies consumption.

Highlights

Illicit consumption of anabolic-androgenic steroids for aesthetic purposes has increased in recent years
O relato de casos, em patologias pouco freqüentes, é fundamental para disseminar e ampliar as informações que auxiliam o clínico a considerar com firmeza esse diagnóstico antes mesmo do não reconhecimento inicial do consumo pelo paciente
Caution for anabolic androgenic steroid use: a case report of multiple organ dysfunction syndrome

Summary

Caso clínico

Hepatotoxicidad por esteroides anabólicos androgénicos, reporte de 2 casos en Uruguay. Hepatotoxicity Induced by Anabolic-Androgenic Steroids, 2 Cases Report in Uruguay. Hepatotoxicidade por anabolizantes esteróides androgênicos, relato de 2 casos no Uruguai. Resumen: El consumo ilícito de esteroides anabólicos androgénicos con fines estéticos ha aumentado en los últimos años y, aunque raro, es causa de hepatotoxicidad. Los casos con daño hepatocelular son más frecuentes, pero los colestásicos son más graves y pueden asociarse a falla renal. Se describe y discuten las historias clínicas de dos hombres jóvenes, deportistas aficionados que consultaron por ictericia y presentaron colestasis e insuficiencia renal. En patologías poco frecuentes, resulta fundamental para difundir y ampliar la información que ayude al clínico a considerar con firmeza este diagnóstico, incluso ante la falta de reconocimiento inicial del consumo por parte del paciente.

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