Abstract
The present study was carried out to evaluate the antioxidant effect of methanol extract of Pandanus odoratissimus lim (MEPO) leaf in wistar albino rats. The animals were grouped differently and administered with Carbon tetrachloride (CCl4) (1.5/kg−1 CCl4 1 ml kg−1 in liquid paraffin 3 doses (i.p) at 72 h interval). The extracts at the doses of 50 and 100 mgkg−1 and Liv 52 25 mg kg−1 were administered to the CCl4 treated rats. The effect of extract and Liv 52 on serum transaminase (GOT, GPT), alkaline phosphatease (ALP), bilirubin and total protein were measured in the rat induced by CCl4. The effect of extract on lipid peroxidation (LPO), Superoxide Dismutase (SOD), Catalase (CAT), Glutathione (GSH) and Vitamin E were estimated. The extract and Liv 52 produced significant (P < 0.05) effect by decreasing the activity of serum enzymes, bilirubin, uric acid and lipid peroxidation and significantly (P < 0.05) increased in the level of SOD, CAT, GSH, Vitamin E and protein. Hence these results suggest that Methanolic extract of Pandanus odoratissimus has potent antioxidant properties.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
