Abstract
As a part of our search for hepatoprotective compounds from Lycium chinense fruits, three new pyrrole derivatives ( 1– 3) were isolated. These compounds and a related synthetic methylated compound ( 4) were evaluated for their biological activity and structure–activity relationship, and compounds 1 and 2 showed hepatoprotective effects comparable to silybin at the concentration of 0.1 μM (64.4 and 65.8%, respectively).
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