Abstract
Taraxacum officinalis (Dandelion) have been used as folk medicines in China, India, and Russia for the treatment of chronic liver diseases. This review focuses exclusively on published literature pertaining to the potential use of Taraxacum officinalis or Dandelion for the treatment of various chronic liver diseases. Dandelion has been tested against various drugs and chemical induced chronic liver diseases in experimental animals and came out with promising results. In vitro studies also confirm the hepatoprotective, antioxidant and anti-inflammatory properties of dandelion. The extensive literature survey reveal the fact that Taraxacum officinalis or dandelion to be safe and the available evidence on the mechanisms of action appears promising, there are currently insufficient d ata from well-conducted clinical trials to recommend it use in patients with alcoholic liver chronic liver disease.
Highlights
The liver is one of the vital organs of human body, being involved in myriad vital functions and regulation of physiological processes
This review focuses exclusively on published literature pertaining to the potential use of Taraxacum officinalis or Dandelion for the treatment of various chronic liver diseases
The extensive literature survey reveal the fact that Taraxacum officinalis or dandelion to be safe and the available evidence on the mechanisms of action appears promising, there are currently insufficient d ata from well-conducted clinical trials to recommend it use in patients with alcoholic liver chronic liver disease
Summary
The liver is one of the vital organs of human body, being involved in myriad vital functions and regulation of physiological processes. The conventional treatments of chronic liver injuries such as fibrosis, cirrhosis, steatosis and chronic hepatitis are frequently inadequate due to side effects caused by various drugs and chemicals. To overcome this problem, current research focused on drugs derived from medicinal plants, due to their richness in flavonoid and ployphenolic compounds have been extensively studied against various drug and chemical induced. Other terpene/sterol compounds include beta-amyrin, taraxasterol, and taraxerol, as well as free sterols (sitosterin, stigmasterin, and phytosterin) structurally related to bile (Koo et al, 2004; Schütz et al, 2006) Presence of these biologically active principles in the TO extract have been attributed for its beneficial effects. The terms Taraxacum officinale and dandelion are generally interchangeably used in the literature
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